EOE Atlas
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Educational purposes only. EOE requires endoscopy with biopsy for diagnosis. Consult a gastroenterologist or allergist for medical advice. This platform aggregates publicly available research data and does not provide medical recommendations.

© 2026 EOE Atlas

Treatment & Diet Guide

Evidence-based treatments, elimination diet protocols, and practical recipes for managing EoE. Always discuss options with your gastroenterologist.

Medical Disclaimer: This information is from peer-reviewed research and should not replace medical advice. Treatment decisions should be made with your healthcare provider.

Dupixent (Dupilumab)

BiologicFDA Approved

FDA-approved biologic that blocks IL-4 and IL-13, key drivers of allergic inflammation in EoE. The first and only biologic approved specifically for EoE.

Success: 60-82%Evidence: Level 1 (RCT)
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Swallowed Topical Corticosteroids

MedicationFDA Approved

Corticosteroids (budesonide or fluticasone) swallowed to coat the esophagus and reduce inflammation directly at the site of disease.

Success: 64-71%Evidence: Level 1 (RCT)
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PPI (Proton Pump Inhibitors)

MedicationFDA Approved

Medications like omeprazole, esomeprazole, or pantoprazole that reduce stomach acid. Often the first-line treatment tried for EoE.

Success: 45-65%Evidence: Level 1 (Meta-analysis)
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Elemental Diet

Dietary

Amino acid-based formula diet that contains no intact proteins, eliminating all potential food allergens. The most effective but most restrictive dietary therapy.

Success: >90%Evidence: Level 2
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Esophageal Dilation

Procedure

Endoscopic procedure to stretch narrowed areas (strictures) of the esophagus. Treats structural complications but not underlying inflammation.

Success: Symptomatic reliefEvidence: Level 2
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